March 2025 - Final report of the FWD AMR-RefLabCap 

Abstract

The service contract aimed to strengthen coordination, support, and capacity in national reference laboratories (NRLs) in public health (PH) for antimicrobial resistance (AMR) in Salmonella and Campylobacter across Europe. It focused on capacity building, enhancing the NRLs’ roles, and modernising diagnostic and typing tests using whole-genome sequencing (WGS). The project established a comprehensive laboratory network and significantly improved the NRLs’ roles and capacity for AMR in both pathogens through targeted support, especially for NRLs with the greatest needs. Key documents and protocols were developed, and external quality assessment schemes and ring trials were organised. These efforts modernised WGS-based diagnostic and typing tests, resulting in more uniform AMR testing. The advancements strengthened laboratory capabilities, improved AMR monitoring, and enhanced PH preparedness.
Future support for NRLs should build on these achievements by refining laboratory procedures, standardising data interpretation, improving communication, and addressing resource gaps through targeted mentoring, comprehensive training, and adequate funding. Clear legal frameworks and external support are crucial for better coordination and support of national laboratory networks. Interdisciplinary collaboration can be improved through joint trainings, data sharing frameworks, and formal agreements. Expanding support to other food and waterborne pathogens and fostering cross-border collaboration will further enhance PH readiness.

Access the full report here:

Final report of the FWD AMR-RefLabCap (pdf)